Povidone-Iodine Solution
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Hebei Keming Medicines Imp. &Exp. Trade Co., Ltd
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Description
Each 200 ml povidone-iodine solution contains 20 g povidone-iodine, equivalent to 2 g available iodine.
Pharmacology
Povidone-lodine is an iodophor in which iodine is bound to the carrier molecule, povidone. The
complex, povidone-iodine, slowly liberates inorganic iodine when in contact with the skin and
mucous membranes. Only a small amount of iodine is released at any one time, giving
Povidone-lodine a lower irritant potential, and longer duration of microbicidal action than
conventional lodine solutions.
Indications
For preoperative and postoperative scrubbing of skin by hospital operating personnel; for
preoperative use on patients as an antiseptic cleanser or for general use as an antiseptic skin
cleanser in the surgery.
Dosage & Administration
Use as often as needed. Always dilute.
Vaginal:
Vaginal candidiasis
Adult: 200 mg given as pessaries.
Topical/Cutaneous:
Treatment and prophylaxis of wound infection
Adult: Apply 0.5-5% topical powders on affected area.
Mouth/Throat:
Oral hygiene
Adult: Rinse mouth with 10 mL of a 0.1% undiluted or diluted solution with an equal amount of
warm water solution for 30 seconds id continued for 14 days.
Child: >6 vears: Same as adult dose.
Mouth/Throat:
Oral candidiasis
Adult: Rinse mouth with 1% mouthwash solution.
Contra-Indications
Sensitivity to povidone-iodine. Not to be used during pregnancy and lactation.
Side Effects & Precautions
The application of povidone-iodine to severe burns or to large areas otherwise denuded of skin
may produce systemic adverse effects associated with iodine. Skin sensitivity may occur.
Hypothyroidism can result, from topical application of povidone-iodine to neonates. Severe
metabolic acidosis may occur in patients suffering from burns covering more than 20% of the
body area. In such cases discontinue the use of povidone-iodine. The activity of povidone-
iodine is reduced in the presence of alkalis.
Drug Interactions
Appears to interfere with other disinfectants, specifically silver sulfadiazine or chlorhexidine,
when used together.
Presentation
Plastic bottle containing 200ml solution.
Storage
Store below 25°C
Protect from light.
Keep out of reach of children.
Expiry Date
3 years